Revealing Genetic Causes of Parkinson’s Disease
Clinical Phenotype of LRRK2 R1441C in 2 Chinese Sisters
Certain variants in LRRK2 have been associated with Parkinson’s disease. While much is known about this association for some variants, knowledge is still sparse for others. In the frame of a CENTOGENE-led clinical study, two patients with the ultra-rare p.R1441C variant were identified and extensively characterized. These findings were published in Neurodegenerative Diseases.